NEET • Chemistry

Reduction

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LiAlH4 Reduction Map

The source lists LiAlH4 reductions across carbonyls and carboxylic acid derivatives.

Starting groupProduct

R−CHOR-CHO

RCH2OHRCH_2OH

R−C(=O)−RR-C(=O)-R

R−CH(OH)−RR-CH(OH)-R

RCOOHRCOOH

R−CH2OHR-CH_2OH

R−C(=O)−O−C(=O)−RR-C(=O)-O-C(=O)-R

2R−CH2OH2R-CH_2OH

R−C(=O)−OR′R-C(=O)-OR'

RCH2OH+R′OHRCH_2OH+R'OH

R−C(=O)−NH2R-C(=O)-NH_2

R−CH2NH2R-CH_2NH_2

R−C(=O)−ClR-C(=O)-Cl

R−CH2OHR-CH_2OH

R−CNR-CN

R−CH2NH2R-CH_2NH_2

reduction ladder
acid derivativescarbonylalcoholalkaneLiAlH4 / NaBH4LiAlH4red P + HI

Notes

  • C=C/C≡CC=C/C{\equiv}C gives no reaction under the listed LiAlH4 map.